Genetic Association of a Gain-of-Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behçet's Disease.
Lourdes Ortiz FernándezPatrick CoitVuslat YilmazSibel P YentürFatma Alibaz-OnerKenan AksuEren ErkenNursen DüzgünGokhan KeserAyse CefleAyten YaziciAndac ErgenErkan AlpsoyCarlo SalvaraniBruno CasaliBünyamin KısacıkIna KötterJörg HenesMuhammet ÇınarArne SchaeferRahime M NohutcuAlexandra ZhernakovaCisca WijmengaFujio TakeuchiShinji HariharaToshikatsu KaburakiMeriam MessediYeong-Wook SongTimuçin KaşifoğluF David CarmonaJoel M GuthridgeJudith A JamesJavier MartinMaría Francisca González EscribanoGüher Saruhan-DireskeneliHaner DireskeneliAmr Hakam SawalhaPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
We performed the largest genetic association study in Behçet's disease to date. Our findings reveal novel putative functional variants associated with the disease and replicate and extend the genetic associations in other loci across multiple ancestries.
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