The Impact of Cytogenetic Aberrations in the Clonal Evolution of Chronic Myeloid Leukemia: A Single-Center Experience Among 450 Turkish Patients (Cohort Study)

Sevgi Işık Gülçin Günden Hava Üsküdar Teke Olga Meltem Akay Yanar Nur Oğuz Davutoğlu Vahap Aslan Mustafa Karagülle Hülya Özen Oğuz Çilingir Sevilhan Artan Beyhan Durak Aras

Published in: Turkish journal of haematology : official journal of Turkish Society of Haematology (2022)

We suggest that cytogenetic aberrations detected in Ph(+) and (-) clones should be a warning sign in terms of treatment and require close observation. The use of cytogenetic methods for the identification of these anomalies is also important.

Keyphrases

chronic myeloid leukemia
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
copy number
prognostic factors
patient reported outcomes
dna methylation
smoking cessation
bioinformatics analysis