Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex.
Anoek L I van LeeuwenElise BeijerRoselique IbelingsNicole A M DekkerMarjolein R A van der SteenJoris J T H RoelofsMatijs van MeursGrietje MolemaCharissa E van den BromPublished in: PloS one (2023)
Female sex seems to protect against renal, but not pulmonary edema in heterozygous Tie2 knock-out mice. This could not be explained by sex dimorphism in the endothelial angiopoietin/Tie2 system.