Selective IL-1 activity on CD8 + T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication.

Bram Van Den Eeckhout Leander Huyghe Sandra Van LintElianne BurgStéphane Plaisance Frank Peelman Anje Cauwels Gilles UzéNiko KleySarah Gerlo Jan Tavernier

Published in: Journal for immunotherapy of cancer (2022)

Our data illustrate that anticancer cellular immunity can be safely promoted with an IL-1β-based AcTakine, which synergizes with other immunotherapies for efficient tumor destruction.

Keyphrases

rheumatoid arthritis
helicobacter pylori infection
big data
helicobacter pylori
drug delivery
deep learning
data analysis