Role of Notch1 in the arterial specification and angiogenic potential of mouse embryonic stem cell-derived endothelial cells.

Jae Kyung ParkTae Wook LeeEun Kyoung DoHye Ji MoonJae-Ho Kim

Published in: Stem cell research & therapy (2018)

These results suggest that Notch1 promotes endothelial maturation and arterial specification during the differentiation of embryonic stem cells to endothelial cells and increases the angiogenic potential of endothelial cells.

Keyphrases

endothelial cells
embryonic stem cells
stem cells
high glucose
vascular endothelial growth factor
cell proliferation
cell fate
human health
mesenchymal stem cells
climate change
bone marrow