Hepatotoxic Dose Thresholds by Positron-Emission Tomography After Yttrium-90 Radioembolization of Liver Tumors: A Prospective Single-Arm Observational Study.
Keith T ChanAdam M AlessioGuy E JohnsonSandeep VaidyaSharon W KwanWayne MonskyAnn E WilsonDavid H LewisSiddharth A PadiaPublished in: Cardiovascular and interventional radiology (2018)
Increasing delivered 90Y dose to non-tumoral liver measured by internal pair-production PET correlates with post-treatment hepatic toxicity. The likelihood of toxicity exceeds 50% at a dose threshold of 54 Gy. ClinicalTrials.gov identifier: NCT02848638.