Inflammation-related immune proteins in maternal plasma as potential predictive biomarkers for rescue cerclage outcome in women with cervical insufficiency.

So Yeon KimKyo Hoon ParkHyeon Ji KimYu Mi KimKwanghee AhnKyong-No Lee

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)

These findings suggest that plasma IGFBP-3, MIP-1α, and S100A8/A9 can represent noninvasive independent biomarkers for identifying women with CI at high risk for SPTB following rescue cerclage. Nonetheless, further in large, multicenter clinical studies should be performed to confirm the clinical value of these biomarkers.

Keyphrases

preterm birth
oxidative stress
clinical trial
pregnant women