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Pharmacotherapy for the prevention of malaria in pregnant women: currently available drugs and challenges.

Brioni R MooreTimothy M E Davis
Published in: Expert opinion on pharmacotherapy (2018)
Alternative drugs or combination therapies to SP for IPTp are desperately required. Dihydroartemisinin-piperaquine and azithromycin-based combinations are showing great promise as potential candidates for IPTp but pharmacokinetic data suggest that dose modification may be required to ensure adequate prophylactic efficacy. If a suitable candidate regimen is not identified in the near future, the success of chemopreventive strategies such as IPTp may be in jeopardy.
Keyphrases
  • pregnant women
  • plasmodium falciparum
  • big data
  • electronic health record
  • current status
  • drug induced
  • machine learning
  • artificial intelligence
  • pregnancy outcomes