Forsythiaside A ameliorates bleomycin-induced pulmonary fibrosis by inhibiting oxidative stress and apoptosis.
Fan YangQinqin ZhangXi WangYingbo HuSuiqing ChenPublished in: Immunity, inflammation and disease (2024)
The results of our study suggested that FA could protect mice against BLM-induced PF by regulating oxidative stress and apoptosis as well as the Epithelial mesenchymal transition pathway.
Keyphrases
- oxidative stress
- diabetic rats
- pulmonary fibrosis
- epithelial mesenchymal transition
- dna damage
- high glucose
- ischemia reperfusion injury
- induced apoptosis
- endoplasmic reticulum stress
- signaling pathway
- cell death
- cell cycle arrest
- drug induced
- transforming growth factor
- type diabetes
- high fat diet induced
- cell proliferation
- insulin resistance
- metabolic syndrome