Tracking muscle wasting and disease activity in facioscapulohumeral muscular dystrophy by qualitative longitudinal imaging.
Mauro MonforteFrancesco LaschenaPierfrancesco OttavianiMaria Rosaria BagnatoAnna PichiecchioGiorgio TascaEnzo RicciPublished in: Journal of cachexia, sarcopenia and muscle (2019)
Our study confirms that STIR+ lesions represent prognostic biomarkers in FSHD and contributes to delineate its radiological natural history, providing useful information for clinical trial design. Given the peculiar muscle-by-muscle involvement in FSHD, MRI represents an invaluable tool to explore the modalities and rate of disease progression.
Keyphrases
- muscular dystrophy
- disease activity
- skeletal muscle
- clinical trial
- rheumatoid arthritis
- systemic lupus erythematosus
- ankylosing spondylitis
- duchenne muscular dystrophy
- magnetic resonance imaging
- high resolution
- juvenile idiopathic arthritis
- healthcare
- systematic review
- study protocol
- health information
- double blind
- social media
- phase iii