Extracellular volume fraction determined by equilibrium contrast-enhanced multidetector computed tomography as a prognostic factor in unresectable pancreatic adenocarcinoma treated with chemotherapy.
Yoshihiko FukukuraYuichi KumagaeRyutaro HigashiHiroto HakamadaKoji TakumiKosei MaemuraMichiyo HigashiKiyohisa KamimuraMasanori NakajoTakashi YoshiuraPublished in: European radiology (2018)
• Tumour aggressiveness and response to therapy are influenced by the extravascular extracellular space. • Extracellular volume (ECV) fraction can be quantified with equilibrium contrast-enhanced CT. • Patients with higher tumour ECV fraction had better prognosis after chemotherapy.
Keyphrases
- contrast enhanced
- computed tomography
- diffusion weighted
- magnetic resonance imaging
- prognostic factors
- locally advanced
- positron emission tomography
- magnetic resonance
- dual energy
- diffusion weighted imaging
- molecular dynamics
- molecular dynamics simulations
- image quality
- rectal cancer
- squamous cell carcinoma
- radiation therapy
- stem cells
- aqueous solution
- bone marrow
- cell therapy
- liver metastases