Early-Onset GI Cancers: Rising Trends, Genetic Risks, Novel Strategies, and Special Considerations.
Emily HarroldAlicia LathamNaveen PemmarajuChristopher H LieuPublished in: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting (2023)
Cancers in young adults (commonly described as early-onset [EO] cancer) represent a group of malignancies that have unique and challenging biology and genetic, treatment, social, and psychological implications. Even more concerning is a rising trend of EO cancers in multiple tumor types. Research and investigation in EO cancers will help elucidate mechanisms of carcinogenesis, differences in biology and response to treatment, and the need for multidisciplinary care to ensure comprehensive treatment and support for young patients.
Keyphrases
- early onset
- late onset
- young adults
- healthcare
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- genome wide
- squamous cell carcinoma
- mental health
- ejection fraction
- copy number
- combination therapy
- peritoneal dialysis
- dna methylation
- climate change
- pain management
- patient reported outcomes
- prognostic factors
- sleep quality