Small airway determinants of airflow limitation in chronic obstructive pulmonary disease.

Vasiliy V PolosukhinSergey S GutorRui-Hong DuBradley W RichmondPierre P MassionPingsheng WuJustin M CatesKim L SandlerStephen I RennardTimothy S Blackwell

Published in: Thorax (2021)

In COPD, loss of radial alveolar attachments in small airways is the pathological feature most closely related to airflow limitation. Destruction of alveolar attachments may be mediated by neutrophilic inflammation.

Keyphrases

chronic obstructive pulmonary disease
oxidative stress
cystic fibrosis
machine learning
lung function