miRSNP rs188493331: A key player in genetic control of microRNA-induced pathway activation in hypertrophic scars and keloids.

Meiqing ChenYuyan PanZhiwei ChenFazhi QiJianying GuYangyang QiuAnqi HeJiaqi Liu

Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)

The study successfully unveils the complex interactions between miRSNPs, miRNAs, genes, and signaling pathways, shedding light on the genetic factors contributing to HS and keloid formation.

Keyphrases

genome wide
signaling pathway
copy number
high glucose
diabetic rats
dna methylation
endothelial cells
gene expression
oxidative stress
pi k akt
transcription factor
platelet rich plasma
induced apoptosis
genome wide identification