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Guidelines for Packaging, Transport, and Storage of Source Cells for Organoids.

Sungin LeeDayeon KwonHan Byeol LeeSooyeon JeonChi Hye ParkTae Sung KimJin Hee LeeIl Ung OhSun-Ju Ahn
Published in: International journal of stem cells (2024)
This paper presents guidelines for the systematic management of packaging, storage, transportation, and traceability of source cells used for organoid research. Given the important role of source cells in organoid studies, it is important to ensure the preservation of their quality and integrity throughout transportation and distribution processes. The proposed guidelines, therefore, call for a cohesive strategy through these stages to minimize the risks of contamination, deterioration, and loss-threats that significantly compromise the safety, efficacy, and efficiency of source cells. Central to these guidelines is the quality control measures that include roles and responsibilities across the entire supply chain, with recommendations specific to packaging materials, transportation facilities, and storage management. Furthermore, the need for an integrated management system is emphasized, spanning from source cell collection to the final application. This system is crucial for maintaining the traceability and accountability of source cells, facilitating the sharing, distribution, and utilization on a global scale, and supporting to advance organoid research and development.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • oxidative stress
  • risk assessment
  • quality control
  • cell proliferation
  • social media
  • single cell
  • human health
  • cell therapy
  • quality improvement