Ficus deltoidea suppresses endothelial activation, inflammation, monocytes adhesion and oxidative stress via NF-κB and eNOS pathways in stimulated human coronary artery endothelial cells.
Amirah Mohd AriffNurul Ain Abu BakarSuhaila Abd MuidEffat OmarNor Hadiani IsmailAbdul Manaf AliNoor Alicezah Mohd KasimHapizah Mohd NawawiPublished in: BMC complementary medicine and therapies (2020)
FD has anti-atherogenic effects, possibly mediated by NF-κB and eNOS pathways; with FDK being the most potent variety. It is potentially beneficial in mitigating atherogenesis.
Keyphrases
- endothelial cells
- oxidative stress
- signaling pathway
- coronary artery
- pi k akt
- high glucose
- lps induced
- induced apoptosis
- diabetic rats
- dna damage
- vascular endothelial growth factor
- ischemia reperfusion injury
- pulmonary artery
- nuclear factor
- dendritic cells
- escherichia coli
- biofilm formation
- cell proliferation
- anti inflammatory
- nitric oxide synthase
- pulmonary arterial hypertension
- staphylococcus aureus
- pseudomonas aeruginosa
- heat shock
- nitric oxide