Morphologic and Genomic Characteristics of Breast Cancers Occurring in Individuals with Lynch Syndrome.

Christopher J Schwartz Edaise M Da Silva Antonio MarraAndrea M GazzoPier SelenicaVikas K RaiDiana MandelkerFresia ParejaMaksym MisyuraTimothy M D'AlfonsoEdi BrogiPamela DrullinskyPedram RazaviMark E Robson Joshua Z DragoHannah Y WenZarina YelskayaBritta WeigeltJinru ShiaJorge S Reis-FilhoHong Zhang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

A subset of breast cancers developing in individuals with Lynch syndrome are etiologically linked to MMRd and may benefit from anti-PD1/PD-L1 immunotherapy.

Keyphrases

case report
copy number
gene expression
young adults
dna methylation