Ticagrelor Does Not Protect Against Endothelial Ischemia-Reperfusion Injury in Patients With Coronary Artery Disease.
Dinos VerouhisMattias EkströmMagnus SettergrenPeder SörenssonJohn PernowNawzad SalehPublished in: Journal of cardiovascular pharmacology and therapeutics (2020)
Chronic ticagrelor treatment in patients 1 year after an ACS does not protect against endothelial ischaemia-reperfusion injury. Nor is it associated with better basal endothelial function compared to after discontinuation of treatment.
Keyphrases
- acute coronary syndrome
- percutaneous coronary intervention
- antiplatelet therapy
- endothelial cells
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- acute myocardial infarction
- cerebral ischemia
- acute ischemic stroke
- brain injury
- atrial fibrillation
- left ventricular
- replacement therapy
- smoking cessation