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Biomarkers of neurodegeneration and glial activation validated in Alzheimer's disease assessed in longitudinal cerebrospinal fluid samples of Parkinson's disease.

Michael BartlMohammed DaknaDouglas GalaskoSamantha J HuttenTatiana ForoudMarian QuanKenneth MarekAndrew SiderowfJonas FranzClaudia TrenkwalderBrit Mollenhauernull null
Published in: PloS one (2021)
Except for αSyn, the additional biomarkers did not differentiate PD and HC, and none showed longitudinal differences, but most markers predict cognitive decline in PD during follow-up.
Keyphrases
  • cerebrospinal fluid
  • cognitive decline
  • mild cognitive impairment
  • neuropathic pain
  • spinal cord injury