Genetic Factors, Brain Atrophy, and Response to Rehabilitation Therapy After Stroke.
Steven C CramerJill SeeBrent LiuMatthew A EdwardsonXiming WangShlomit Radom-AizikFadia HaddadBabak ShahbabaSteven L WolfAlexander W DromerickCarolee J WinsteinPublished in: Neurorehabilitation and neural repair (2021)
met polymorphism was associated with cerebral atrophy at baseline, echoing findings in healthy subjects, and suggesting an endophenotype. The ApoE ε4 polymorphism was associated with younger age at stroke onset, echoing findings in Alzheimer's disease and suggesting a common biology. Genetic associations provide insights useful to understanding the biology of outcomes after stroke.