Antiretroviral therapy uptake and predictors of virological failure in patients with HIV receiving first-line and second-line regimens in Johannesburg, South Africa: a retrospective cohort data analysis.
Siphamandla Bonga GumedeFrancois VenterJohn de WitAnnemarie WensingSamanta Tresha Lalla-EdwardPublished in: BMJ open (2022)
Patients on first-line regimens had higher VL suppression rates and were more likely to remain in care than those on a second-line regimen. Being younger and having low CD4 cell counts were associated with poor outcomes, suggesting priority groups for ART adherence support.
Keyphrases
- antiretroviral therapy
- hiv positive
- hiv infected
- south africa
- data analysis
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- end stage renal disease
- healthcare
- ejection fraction
- newly diagnosed
- chronic kidney disease
- palliative care
- peritoneal dialysis
- cell therapy
- type diabetes
- single cell
- men who have sex with men
- hepatitis c virus
- patient reported outcomes
- hiv testing
- pain management
- peripheral blood
- adipose tissue
- metabolic syndrome
- weight loss
- insulin resistance
- patient reported