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Antiretroviral therapy uptake and predictors of virological failure in patients with HIV receiving first-line and second-line regimens in Johannesburg, South Africa: a retrospective cohort data analysis.

Siphamandla Bonga GumedeFrancois VenterJohn de WitAnnemarie WensingSamanta Tresha Lalla-Edward
Published in: BMJ open (2022)
Patients on first-line regimens had higher VL suppression rates and were more likely to remain in care than those on a second-line regimen. Being younger and having low CD4 cell counts were associated with poor outcomes, suggesting priority groups for ART adherence support.
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