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Inhibitory effects of Eplerenone on angiogenesis via modulating SGK1/TGF-β pathway in contralateral kidney of CKD pregnancy rats.

Wenping ZhouChang XuJieqi NiuYunzhao XiongZhen HeHepeng XuMengjuan ZhangHongshuang WangQingyou XuXiangting WangZheng Wang
Published in: Cellular signalling (2024)
Eplerenone inhibits renal angiogenesis by blocking the SGK-1/TGFβ signal transduction pathway, thereby inhibiting the phenotypic transformation of endothelial cells, slowing down renal fibrosis, and reducing kidney damage caused by pregnancy.
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