Surgical options for glycaemic control in Type 1 diabetes.
Kai Tai Derek YeungM ReddyS PurkayasthaPublished in: Diabetic medicine : a journal of the British Diabetic Association (2019)
In recent years, bariatric surgery, also referred to as metabolic surgery, has become the most successful treatment option in those with Type 2 diabetes and obesity. There are some similarities in the pathological pathways in Type 1 and Type 2 diabetes, but the use of surgery in Type 1 diabetes remains unestablished and controversial. The treatment and management of Type 1 diabetes can be very challenging but recent advances in surgical interventions and technology has the potential to expand and optimize treatment options. This review discusses the current status of some surgical options available to people with Type 1 diabetes. These include implantable continuous glucose monitoring systems, continuous intraperitoneal insulin infusion pumps, closed-loop insulin delivery systems (also known as the artificial pancreas system) utilizing the latter two modalities of glucose monitoring and insulin delivery, and bariatric or metabolic surgery. Whole pancreas and islet transplantation are beyond the scope of this review but are briefly discussed.
Keyphrases
- type diabetes
- glycemic control
- minimally invasive
- coronary artery bypass
- bariatric surgery
- weight loss
- insulin resistance
- cardiovascular disease
- surgical site infection
- current status
- physical activity
- stem cells
- metabolic syndrome
- mesenchymal stem cells
- risk assessment
- skeletal muscle
- weight gain
- climate change
- high fat diet induced
- bone marrow
- cell therapy
- coronary artery disease
- roux en y gastric bypass