Development and validation of prognostic gene signature for basal-like breast cancer and high-grade serous ovarian cancer.

Yi ZhangJianfang LiuPraveen-Kumar Raj-KumarLori A SturtzAnupama Praveen-KumarHoward H YangMaxwell P LeeJ Leigh Fantacone-CampbellJeffrey A HookeAlbert J KovatichCraig D ShriverHai Hu

Published in: Breast cancer research and treatment (2020)

A gene signature was identified to predict recurrence in BLBC and HGSOC patients. With further validation, this signature may provide an additional prognostic tool for clinicians to better manage BLBC, many of which are triple-negative and HGSOC patients who are currently difficult to treat.

Keyphrases

high grade
end stage renal disease
low grade
ejection fraction
genome wide
copy number
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
genome wide identification
young adults
transcription factor