Iron leakage owing to blood-brain barrier disruption in small vessel disease CADASIL.

Yuto UchidaHirohito KanKeita SakuraiNobuyuki AraiShohei InuiSusumu KobayashiDaisuke KatoYoshino UekiNoriyuki Matsukawa

Published in: Neurology (2020)

This study showed that cerebral iron burden was associated with regional BBB permeability and cognitive dysfunction in patients with CADASIL, highlighting the potential of these imaging techniques as auxiliary biomarkers to monitor the course of small vessel disease.

Keyphrases

blood brain barrier
cerebral ischemia
high resolution
risk factors
iron deficiency
mass spectrometry
human health