Single nCounter assay for prediction of MYCN amplification and molecular classification of medulloblastomas: a multicentric study.

Daniel Antunes MorenoLuciane Sussuchi da SilvaMaicon Fernando ZanonMurilo BonatelliFlávia Escremim de PaulaMarcus de Medeiros MatsushitaGustavo Ramos TeixeiraIara Viana Vidigal SantanaFabiano SaggioroLuciano NederJoão N StavaleSuzana Maria Fleury MalheirosMatheus LimaGlaucia Noeli Maroso HajjHernan Garcia-RivelloSilvia ChristiansenSusana NunesMaria João Gil da CostaMaria José SoaresJorge PinheiroCarlos Almeida JuniorBruna Minniti MançanoRui Manuel Vieira Reis

Published in: Journal of neuro-oncology (2022)

We successfully stratified medulloblastoma molecular subgroups and predicted MYCN amplification using a single nCounter assay without the requirement of additional biological tissue, costs, or bench time.

Keyphrases

high throughput
nucleic acid
machine learning
deep learning