Clinicopathological Characteristics and Outcomes of Anal Squamous Cell Carcinoma Patients With and Without HIV Infection in Sub-Saharan Africa.
Emmanuel MdumaNazima DharseeKandali SamwelChacha J MwitaSalum J LidengePublished in: JCO global oncology (2023)
Patients with anal SCC in Tanzania present mainly with locally advanced disease associated with high HIV prevalence. In this cohort, the SCC grade was independently associated with treatment outcomes unlike other factors such as HIV coinfection.
Keyphrases
- antiretroviral therapy
- squamous cell carcinoma
- locally advanced
- hiv positive
- hiv infected
- human immunodeficiency virus
- hiv testing
- hiv aids
- hepatitis c virus
- men who have sex with men
- high grade
- rectal cancer
- neoadjuvant chemotherapy
- risk factors
- radiation therapy
- phase ii study
- south africa
- lymph node metastasis
- open label
- lymph node
- study protocol