Tumor heterogeneity, aggressiveness, and immune cell composition in a novel syngeneic PSA-targeted Pten knockout mouse prostate cancer (MuCaP) model.

Petra W van DuijnRute B MarquesAngelique C J Ziel-van der MadeHanneke J A A van ZoggelAshraf AghaiCor BerrevoetsReno DebetsGuido JensterJan TrapmanThomas A Kirkland

Published in: The Prostate (2018)

Collectively, we present here a well-defined MuCaP platform of in vitro and in vivo mouse prostate cancer models that may support preclinical assessment of (immune)-therapies for prostate cancer.

Keyphrases

prostate cancer
radical prostatectomy
stem cells
single cell
cancer therapy