Identification of risk factors for adverse drug reactions in a pharmacovigilance database.
Sofia AttelindNiclas ErikssonAnders SundströmMia WadeliusPär HallbergPublished in: Pharmacoepidemiology and drug safety (2023)
We demonstrated that data mining within a pharmacovigilance database identifies known risk factors for DOAC bleeding, and potential risk factors such as dementia and atrial fibrillation. We propose that the method could be used in pharmacovigilance for identification of potential ADR risk factors that merit further evaluation.
Keyphrases
- adverse drug
- risk factors
- electronic health record
- atrial fibrillation
- direct oral anticoagulants
- emergency department
- drug induced
- mild cognitive impairment
- bioinformatics analysis
- heart failure
- left atrial
- oral anticoagulants
- left atrial appendage
- percutaneous coronary intervention
- big data
- mitral valve
- risk assessment
- acute coronary syndrome
- clinical evaluation