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Retinoids in the treatment of photoageing: A histological study of topical retinoid efficacy in black skin.

P HalaiO KissR WangA L ChienS KangC O'ConnorM BellChristopher Ernest Maitland GriffithsR E B WatsonAbigail K Langton
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2024)
This study confirms that topical ATRA has utility for the repair of photoaged black skin and that ROL induces comparable effects on epidermal and dermal remodelling, albeit over a longer timeframe. The effects of topical retinoids on black photoaged skin are similar to those reported for white photoaged skin and suggest conserved biology in relation to repair of UVR-induced damage. Further investigation of topical retinoid efficacy in daily use is warranted for black skin.
Keyphrases
  • wound healing
  • soft tissue
  • oxidative stress
  • physical activity
  • transcription factor
  • diabetic rats
  • combination therapy
  • replacement therapy