CD44v8-10 is a marker for malignant traits and a potential driver of bone metastasis in a subpopulation of prostate cancer cells.

Rosaria A FontanellaSilvia SideriChiara Di StefanoAngiolina CatizoneSilvia Di AgostinoDaniela F AngeliniGisella GuerreraLuca BattistiniGiulia BattafaranoAndrea Del FattoreAntonio Francesco CampeseFabrizio PadulaPaola De Cesaris Antonio FilippiniAnna Riccioli

Published in: Cancer biology & medicine (2021)

CD44v8-10 could represent a marker of a more aggressive bone metastatic PC population exerting a driver role in osteomimicry in bone. A novel link between TAZ and CD44v8-10 is also shown.

Keyphrases

bone mineral density
soft tissue
bone loss
bone regeneration
nk cells
small cell lung cancer
postmenopausal women
genome wide
gene expression
body composition
human health