Diagnostic accuracy of C-reactive protein, procalcitonin and neutrophils for the early detection of anastomotic leakage after colorectal resection: a multicentric, prospective study.
Angela Sala HernandezMatteo FrassonAlvaro García-GraneroDavid Hervás MarínBegoña Laiz MarroRicardo Alonso PardoInés Aldrey CaoJosé Antonio Alvarez PerezCristina Roque CastellanoJose María García GonzálezJanine Tabet AlmeidaEduardo García-Graneronull nullPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)
On the fourth postoperative day, CRP was the most reliable marker for excluding AL. Its high negative predictive value, especially after laparoscopic resection, allows for safe hospital discharge on the fourth postoperative day. The routine use of procalcitonin or neutrophil counts does not seem to increase the diagnostic accuracy.