Metagenomic Next-generation Sequencing for Pathogen Identification in Bronchoalveolar Lavage Fluid From Neonates Receiving Extracorporeal Membrane Oxygenation.
Yi-Rong ZhengXiu-Hua ChenQiang ChenHua CaoPublished in: The Pediatric infectious disease journal (2024)
Compared with CMT, mNGS can detect pathogens earlier and more sensitively, and may play an important role in ECMO-supported neonatal pneumonia pathogen detection and optimization of antibiotic therapy.
Keyphrases
- extracorporeal membrane oxygenation
- respiratory failure
- acute respiratory distress syndrome
- candida albicans
- gram negative
- copy number
- loop mediated isothermal amplification
- mechanical ventilation
- antibiotic resistance genes
- label free
- stem cells
- intensive care unit
- microbial community
- multidrug resistant
- genome wide
- community acquired pneumonia
- preterm infants
- smoking cessation
- circulating tumor cells