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A library of quantitative markers of seizure severity.

Sarah J GascoigneLeonard WaldmannGabrielle M SchroederMariella PanagiotopoulouJess BlickwedelFahmida ChowdhuryAlison CronieBeate DiehlJohn S DuncanJennifer FalconerRyan FaulderYu GuanVeronica LeachShona LivingstoneChristoforos PapasavvasRhys Huw ThomasKevin WilsonPeter Neal TaylorYujiang Wang
Published in: Epilepsia (2023)
We demonstrate the feasibility of using quantitative iEEG markers to measure seizure severity. Our quantitative markers distinguish between seizure types and are therefore sensitive to established qualitative differences in seizure severity. Our results also suggest that seizure severity is modulated over different timescales. We envisage that our proposed seizure severity library will be expanded and updated in collaboration with the epilepsy research community to include more measures and modalities.
Keyphrases
  • temporal lobe epilepsy
  • high resolution
  • healthcare
  • systematic review
  • mental health
  • mass spectrometry