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Ultra-low-coverage genome-wide association study-insights into gestational age using 17,844 embryo samples with preimplantation genetic testing.

Shumin LiBin YanThomas K T LiJianliang LuYifan GuYueqiu TanFei GongTak-Wah LamPingyuan XieYuexuan WangGe LinRuibang Luo
Published in: Genome medicine (2023)
This study not only demonstrates that ulcWGS could achieve relatively high accuracy of adequate genotype imputation and is capable of GWAS, but also provides insights into the associations between gestational age and genetic variations of the fetal embryos from Chinese population.
Keyphrases
  • body mass index
  • gestational age
  • genome wide association study
  • birth weight
  • weight gain
  • preterm birth
  • genome wide
  • healthcare
  • copy number
  • dna methylation
  • weight loss
  • pregnancy outcomes