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Transcriptional profiling of human cartilage endplate cells identifies novel genes and cell clusters underlying degenerated and non-degenerated phenotypes.

Kyle KuchynskyPatrick StevensAmy HiteWilliam XieKhady DiopShirley TangMaciej PietrzakSafdar KhanBenjamin WalterDevina Purmessur
Published in: Arthritis research & therapy (2024)
This thorough analysis using RNA sequencing methods highlighted numerous differences between non-degenerated and degenerated CEP cells, the phenotypic heterogeneity of CEP cells, and several pathways of interest that may be relevant in CEP degeneration.
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