Macrophage ICAM-1 functions as a regulator of phagocytosis in LPS induced endotoxemia.

Hanhui ZhongHaitao LinQiongni PangJinling ZhuangXiaolei LiuXiaolian LiJinghua LiuLiangqing Zhang

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2021)

This study demonstrates that the mechanism of ICAM-1-mediated macrophage phagocytosis is depending on TLR4-mediated ROS production and provides significant light on macrophage ICAM-1 in endotoxemia.

Keyphrases

lps induced
inflammatory response
adipose tissue
toll like receptor
dna damage
transcription factor
reactive oxygen species