Limited additive value of the Ki-67 proliferative index on patient survival in World Health Organization-classified pulmonary carcinoids.
Dorian R A SwartsMartina RudeliusSandra M H ClaessenJack P CleutjensStefan SeidlMarco VolanteFrans C S RamaekersErnst J M SpeelPublished in: Histopathology (2016)
Our study demonstrates that, although Ki-67 is a strong prognostic factor for pulmonary carcinoids, its usefulness in addition to histopathology in prediction of prognosis is limited. None the less, it may have additional value, especially in cases that are difficult to classify, in combination with histopathology and other molecular markers.