Model-Informed Precision Dosing of Tacrolimus: A Systematic Review of Population Pharmacokinetic Models and a Benchmark Study of Software Tools.

Yannick Hoffert Nada Dia Tim Vanuytsel Robin Vos Dirk R J Kuypers Johan Van Cleemput Jef Verbeek Erwin Dreesen

Published in: Clinical pharmacokinetics (2024)

Our work provides a comprehensive overview of the landscape of available tacrolimus population pharmacokinetic models and model-informed precision dosing software modules. Our simulation tool allows an interactive thorough exploration of covariates on exposure and target attainment.

Keyphrases

data analysis
single cell