Exploring the role of copine 1 in human colorectal cancer: investigating its association with tumorigenesis and metastasis.
Jin Kwon LeeSeung-Jun LeeYoung-Sool HahYeong-Ho JiYoung-Tae JuYoung Joon LeeChi Young JeongJu-Yeon KimJi Ho ParkJae-Myung KimChi-Young JeongHan-Gil KimSeung Jin KwagPublished in: Annals of surgical treatment and research (2023)
CPNE1 plays a crucial role in promoting tumorigenesis and metastasis in human CRC. By regulating the cell cycle and EMT, CPNE1 influences critical cellular processes at the membrane-cytoplasm interface. These results provide valuable insights into the potential development of novel therapeutic strategies for CRC targeting CPNE1.