Is the St. George's Respiratory Questionnaire an Appropriate Measure of Symptom Severity and Activity Limitations for Clinical Trials in COPD? Analysis of Pooled Data from Five Randomized Clinical Trials.

Angely LoubertAntoine Regnault Juliette Meunier Florian S GutzwillerStéphane A Regnier

Published in: International journal of chronic obstructive pulmonary disease (2020)

Our results indicated that SGRQ may not be an appropriate instrument to measure symptom severity or activity limitations in patients with COPD. Hence, there is a need to develop other relevant PRO instruments that can be used in conjunction with SGRQ to provide a holistic assessment of the health status of COPD patients in clinical research.

Keyphrases

chronic obstructive pulmonary disease
lung function
clinical trial
patient reported
end stage renal disease
patient reported outcomes
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
cystic fibrosis
air pollution
anti inflammatory
open label
phase ii
data analysis