C/EBPβ: A transcription factor associated with the irreversible progression of Alzheimer's disease.

Qing YaoChubing LongPengcheng YiGuangyong ZhangWei WanXiuqin RaoJun YingWeidong LiangFuzhou Hua

Published in: CNS neuroscience & therapeutics (2024)

The overexpression of C/EBPβ accelerates the irreversible progression of AD pathophysiology. Additionally, C/EBPβ plays a crucial role in mediating multiple pathways linked to AD pathology, some of which engender vicious cycles, leading to the establishment of feedback mechanisms. To sum up, targeting C/EBPβ could hold promise as a therapeutic strategy not only for AD but also for other degenerative diseases.

Keyphrases

transcription factor
cell proliferation
cognitive decline
cancer therapy
dna binding
machine learning
drug delivery
artificial intelligence
mild cognitive impairment