Association rules method and big data: Evaluating frequent medication combinations associated with fractures in older adults.
Prasad S NishtalaTe-Yuan ChyouFabian HeldDavid G Le CouteurDanijela GnjidicPublished in: Pharmacoepidemiology and drug safety (2018)
The association rules method identified medication exposure combinations containing psychotropic medications and codeine are frequently associated with fractures. This novel methodology applied to big data can be an important tool to ascertain medication combinations associated with adverse drug events.