Brain iron deposition is linked with cognitive severity in Parkinson's disease.
George Edward Calver ThomasLouise Ann LeylandAnette-Eleonore SchragAndrew John LeesJulio Acosta-CabroneroRimona Sharon WeilPublished in: Journal of neurology, neurosurgery, and psychiatry (2020)
Brain tissue iron, measured using QSM, can track cognitive involvement in PD. This may be useful to detect signs of early cognitive change to stratify groups for clinical trials and monitor disease progression.