Role of DOAC plasma concentration on perioperative blood loss and transfusion requirements in patients with hip fractures.

Hannah HoferDaniel OberladstätterChristoph J SchlimpWolfgang VoelckelJohannes ZipperleChris LockieOliver GrottkeMarcin OsuchowskiHerbert Schöchl

Published in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2022)

No strong association between the DOAC plasma levels and perioperative blood loss was detected. Higher transfusion rates in patients with DOAC levels ≥ 80 ng/mL were primarily related to lower admission haemoglobin levels. DOAC concentration measurement is feasible and expedites time to surgery.

Keyphrases

direct oral anticoagulants
cardiac surgery
venous thromboembolism
atrial fibrillation
acute kidney injury
patients undergoing
minimally invasive
emergency department
coronary artery bypass
sickle cell disease
percutaneous coronary intervention