Login / Signup

Amyloid β-induced impairments on mitochondrial dynamics, hippocampal neurogenesis, and memory are restored by phosphodiesterase 7 inhibition.

Fernando BartolomeMacarena de la CuevaConsuelo PascualDesiree AntequeraTamara FernandezCarmen GilAna MartinezEva Carro
Published in: Alzheimer's research & therapy (2018)
Here, we show new therapeutic effects of the PDE7 inhibitor, confirming S14 as a potential therapeutic drug for AD.
Keyphrases
  • cerebral ischemia
  • diabetic rats
  • oxidative stress
  • high glucose
  • drug induced
  • working memory
  • endothelial cells
  • emergency department
  • adverse drug
  • blood brain barrier
  • brain injury