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The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias.

Samir Abu-RumeilehSabina CapellariMichelangelo Stanzani-MaseratiBarbara PolischiPaolo MartinelliPaola CaroppoAnna LadoganaPiero Parchi
Published in: Alzheimer's research & therapy (2018)
The present data indicate that CSF NfL and t-tau levels reflect distinct pathophysiological mechanisms of neurodegeneration and support the clinical use of NfL as a fast screening biomarker for the differential diagnosis of atypical/rapidly progressive NDs.
Keyphrases
  • cerebrospinal fluid
  • multiple sclerosis
  • electronic health record
  • big data