Late-onset Huntington's disease with 40-42 CAG expansion.

Elisa CapiluppiLuca RomanoPaola ReboraLorenzo NanettiAnna CastaldoCinzia GelleraCaterina MariottiAntonella MacerolloM Giuliana Cislaghi

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)

There were no clinical differences between CO and LO subgroups with 40-42 CAG expansion. There is a need of further studies on environmental as well genetic variables modifying the age at onset.

Keyphrases

late onset
early onset
genome wide
copy number
case control
gene expression
dna methylation
climate change