Brain Imaging-Guided Analysis Reveals DNA Methylation Profiles Correlated with Insular Surface Area and Alcohol Use Disorder.

Yihong ZhaoYongchao GeZhi-Liang Zheng

Published in: Alcoholism, clinical and experimental research (2019)

We have identified 36 insular surface area- and AUD-correlated protein-coding genes that are either known to be AUD- or alcohol-related or not yet reported by prior studies. Therefore, our study suggests that the brain imaging-guided epigenetic analysis has a potential of identifying possible epigenetic mechanisms involved in AUD.

Keyphrases

alcohol use disorder
dna methylation
genome wide
gene expression
high resolution
white matter
resting state
cerebral ischemia
small molecule
multiple sclerosis
amino acid
binding protein
case control