Unravelling the dorsal periaqueductal grey matter NMDA receptors relevance in the nitric oxide-mediated panic‑like behaviour and defensive antinociception organised by the anterior hypothalamus of male mice.
Luiz Luciano Falconi-SobrinhoTayllon Dos Anjos-GarciaPaloma Molina HernandesBruno Mangili de Paula RodriguesRafael Carvalho AlmadaNorberto Cysne CoimbraPublished in: Psychopharmacology (2023)
These findings suggest that the panic-like freezing and oriented escape defensive behaviours, and fear-induced antinociception elicited by intra-AH microinjections of SIN-1 depend on the activation of dPAG NMDA receptors.